Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
About this item
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Author / Creator
Publisher
Cambridge: eLife Science Publications, Ltd
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Language
English
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Publisher
Cambridge: eLife Science Publications, Ltd
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Scope and Contents
Contents
Many bacteria encode multiple toxin–antitoxin (TA) systems targeting separate, but closely related, cellular functions. The toxin of the
Escherichia coli hipBA
system, HipA, is a kinase that inhibits translation via phosphorylation of glutamyl-tRNA synthetase. Enteropathogenic
E. coli
O127:H6 encodes the
hipBA
-like, tripartite TA...
Alternative Titles
Full title
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
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TN_cdi_doaj_primary_oai_doaj_org_article_b7fee1b322314a3ab61883541b74fd2d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b7fee1b322314a3ab61883541b74fd2d
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.90400
