Upregulation of CD22 by Chidamide promotes CAR T cells functionality
Upregulation of CD22 by Chidamide promotes CAR T cells functionality
About this item
Full title
Author / Creator
Yang, Xin , Yu, Qiuxia , Xu, Hao and Zhou, Jianfeng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Treatment failure or relapse due to tumor escape caused by reduction in target antigen expression has become a challenge in the field of CART therapy. Target antigen density is closely related to the effectiveness of CART therapy, and reduced or lost target antigen expression limits the efficacy of CART therapy and hinders the durability of CAR T c...
Alternative Titles
Full title
Upregulation of CD22 by Chidamide promotes CAR T cells functionality
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b92b3a4dbae94e29a65633b3c3a0c3ad
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b92b3a4dbae94e29a65633b3c3a0c3ad
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-00227-4
