Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitoch...
Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Proper lipid metabolism is crucial to maintain alveolar epithelial cell (AEC) function, and excessive AEC death plays a role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The mRNA expression of fatty acid synthase (FASN), a key enzyme in the production of palmitate and other fatty acids, is downregulated in the lungs of IPF patients....
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Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_ba5daa9f8a354328bf9d18a2a606bd0e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba5daa9f8a354328bf9d18a2a606bd0e
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-36009-3
