NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells
NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Combination therapies or multi-targeted drugs have been pointed out as an option to prevent the emergence of resistant clones, which could make long-term treatment more effective and translate into better clinical outcomes for cancer patients. The NT157 compound is a synthetic tyrphostin that leads to long-term inhibition of IGF1R/IRS1-2-, STAT3- a...
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NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_ba889964acb4478cb6c8e5da3c7fd7b1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ba889964acb4478cb6c8e5da3c7fd7b1
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-21419-6
