Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We report that supplementation of glutamine alone is s...
Alternative Titles
Full title
Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_baa64e48583c47e993cde6f66f813394
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_baa64e48583c47e993cde6f66f813394
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00369-y
