Log in to save to my catalogue

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_baa64e48583c47e993cde6f66f813394

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

About this item

Full title

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-08, Vol.8 (1), p.338-10, Article 338

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on the regulation of mTORC1, a critical kinase that regulates cell growth and proliferation. We report that supplementation of glutamine alone is s...

Alternative Titles

Full title

Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_baa64e48583c47e993cde6f66f813394

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_baa64e48583c47e993cde6f66f813394

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00369-y

How to access this item