Intratumoral CXCL13+CD8+T cell infiltration determines poor clinical outcomes and immunoevasive cont...
Intratumoral CXCL13+CD8+T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinoma
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Author / Creator
Dai, Siyuan , Zeng, Han , Liu, Zhaopei , Jin, Kaifeng , Jiang, Wenbin , Wang, Zewei , Lin, Zhiyuan , Xiong, Ying , Wang, Jiajun , Chang, Yuan , Bai, Qi , Xia, Yu , Liu, Li , Zhu, Yu , Xu, Le , Qu, Yang , Guo, Jianming and Xu, Jiejie
Publisher
England: BMJ Publishing Group LTD
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Language
English
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Publisher
England: BMJ Publishing Group LTD
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Contents
BackgroundChemokine (C-X-C motif) ligand 13 (CXCL13) was known as a selective chemotaxis for B cells, a product of follicular helper CD4+T cells (TFH) and a contributor to tertiary lymphoid structures (TLS). Although secretion and function of CXCL13 produced by TFH have been deeply explored, the immune function and prognostic significance of CXCL13...
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Full title
Intratumoral CXCL13+CD8+T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_baab847d8bea4f15b4bd2b884e584010
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_baab847d8bea4f15b4bd2b884e584010
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001823
