Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alter...
Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Recent advance in cancer research sheds light on the contribution of mitochondrial respiration in tumorigenesis, as they efficiently produce ATP and oncogenic metabolites that will facilitate cancer cell growth. Here we show that a stabilizing factor for mitochondrial supercomplex assembly, COX7RP/COX7A2L/SCAF1, is abundantly expressed in clinical...
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Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance
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TN_cdi_doaj_primary_oai_doaj_org_article_bad10cef981742fbab5db0b208752c93
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bad10cef981742fbab5db0b208752c93
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12124-6
