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Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc34cc152564482a90c65b2b3ba4e09a

Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

About this item

Full title

Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-05, Vol.8 (1), p.1-9, Article 7337

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D
4
receptor (D
4
R), which is expressed in the caudate putamen (CPu), mainly counteracts morphine-induced alterations in several molecul...

Alternative Titles

Full title

Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bc34cc152564482a90c65b2b3ba4e09a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc34cc152564482a90c65b2b3ba4e09a

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-25604-4

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