Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progr...
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Hemorrhage and hemolysis with subsequent heme release are implicated in many pathologies. Endothelial cells (ECs) encounter large amount of free heme after hemolysis and are at risk of damage from exogenous heme. Here we show that hemorrhage aggravates endoplasmic reticulum (ER) stress in human carotid artery plaques compared to healthy controls or...
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Full title
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression
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TN_cdi_doaj_primary_oai_doaj_org_article_bc71b043d333425e8f8bbfb10cf802ad
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bc71b043d333425e8f8bbfb10cf802ad
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-89713-3
