Abacavir inhibits but does not cause self-reactivity to HLA-B57:01-restricted EBV specific T cell re...
Abacavir inhibits but does not cause self-reactivity to HLA-B57:01-restricted EBV specific T cell receptors
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pre-existing pathogen-specific memory T cell responses can contribute to multiple adverse outcomes including autoimmunity and drug hypersensitivity. How the specificity of the T cell receptor (TCR) is subverted or seconded in many of these diseases remains unclear. Here, we apply abacavir hypersensitivity (AHS) as a model to address this question b...
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Full title
Abacavir inhibits but does not cause self-reactivity to HLA-B57:01-restricted EBV specific T cell receptors
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TN_cdi_doaj_primary_oai_doaj_org_article_bcdd7ff4c80c420a8da2e27c19a3a258
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bcdd7ff4c80c420a8da2e27c19a3a258
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03058-9
