A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific m...
A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific memory B cells to evolve
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Understanding the natural evolution and structural changes involved in broadly neutralizing antibody (bnAb) development holds great promise for improving the design of prophylactic influenza vaccines. Here we report an haemagglutinin (HA) stem-directed bnAb, 3I14, isolated from human memory B cells, that utilizes a heavy chain encoded by the
IGH...
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Full title
A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific memory B cells to evolve
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TN_cdi_doaj_primary_oai_doaj_org_article_bdbf5311bd834c67bd4c3bb2bd03af22
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bdbf5311bd834c67bd4c3bb2bd03af22
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12780
