Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the agg...
Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
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Cambridge: eLife Sciences Publications Ltd
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Language
English
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Cambridge: eLife Sciences Publications Ltd
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Contents
Mitochondria are organelles with their own genomes, but they rely on the import of nuclear-encoded proteins that are translated by cytosolic ribosomes. Therefore, it is important to understand whether failures in the mitochondrial uptake of these nuclear-encoded proteins can cause proteotoxic stress and identify response mechanisms that may counter...
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Full title
Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_bde42a68f5f14029a3273e815c975f47
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bde42a68f5f14029a3273e815c975f47
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.65484
