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468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activati...

468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be6e03e567ca486f9b68f511ad6c41df

468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activation and enhanced clinical efficacy irrespective of PD-L-1 status

About this item

Full title

468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activation and enhanced clinical efficacy irrespective of PD-L-1 status

Publisher

London: BMJ Publishing Group Ltd

Journal title

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A522-A526

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

BackgroundToripalimab is a PD-1 targeting humanized IgG4 monoclonal antibody (mAb) that is currently pending approval by US Food and Drug Administration (FDA) for first-line treatment of nasopharyngeal carcinoma (NPC) in combination with chemotherapy. While currently approved PD-1 mAbs have demonstrated significant clinical benefit particularly in...

Alternative Titles

Full title

468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activation and enhanced clinical efficacy irrespective of PD-L-1 status

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_be6e03e567ca486f9b68f511ad6c41df

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be6e03e567ca486f9b68f511ad6c41df

Other Identifiers

E-ISSN

2051-1426

DOI

10.1136/jitc-2023-SITC2023.0468

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