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ArticlesPeer ReviewedFull Text
First FDA Approval Agnostic of Cancer Site — When a Biomarker Defines the Indication
Author / Creator:Lemery, Steven ; Keegan, Patricia ; Pazdur, Richard
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-10, Vol.377 (15), p.1409-1412
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ArticlesPeer ReviewedFull Text
FDA Supplemental Approval Summary: Lenvatinib for the Treatment of Unresectable Hepatocellular Carcinoma
Author / Creator:Nair, Abhilasha ; Reece, Kelie ; Donoghue, Martha B. ; Yuan, Weishi (Vivian) ; Rodriguez, Lisa ; Keegan, Patricia ; Pazdur, Richard
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:The oncologist (Dayton, Ohio), 2021-03, Vol.26 (3), p.e484-e491
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Newspaper ArticlesFull Text
KEEGAN, Patricia G
Publisher:Hartford, Conn: Tribune Publishing Company, LLC
Journal title:The Hartford courant, 2013-10-08
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ArticlesPeer ReviewedFull Text
Systematic Review of PD‐1/PD‐L1 Inhibitors in Oncology: From Personalized Medicine to Public Health
Author / Creator:Chang, Elaine ; Pelosof, Lorraine ; Lemery, Steven ; Gong, Yutao ; Goldberg, Kirsten B. ; Farrell, Ann T. ; Keegan, Patricia ; Veeraraghavan, Janaki ; Wei, Guo ; Blumenthal, Gideon M. ; Amiri‐Kordestani, Laleh ; Singh, Harpreet ; Fashoyin‐Aje, Lola ; Gormley, Nicole ; Kluetz, Paul G. ; Pazdur, Richard ; Beaver, Julia A. ; Theoret, Marc R.
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:The oncologist (Dayton, Ohio), 2021-10, Vol.26 (10), p.e1786-e1799
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ArticlesPeer ReviewedFull Text
Comparison of iRECIST versus RECIST V.1.1 in patients treated with an anti-PD-1 or PD-L1 antibody: pooled FDA analysis
Author / Creator:Mulkey, Flora ; Theoret, Marc R ; Keegan, Patricia ; Pazdur, Richard ; Sridhara, Rajeshwari
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-02, Vol.8 (1), p.e000146
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ArticlesPeer ReviewedFull Text
468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activation and enhanced clinical efficacy irrespective of PD-L-1 status
Author / Creator:Ravindranathan, Sruthi ; Wang, Xiaoguang ; Chin, Daniel J ; Tseng, Su-Yi ; Klakamp, Scott ; Widmann, Kate ; Kapoor, Varun ; Vexler, Vladimir ; Keegan, Patricia ; Yao, Sheng ; Khare, Sanjay D ; LaVallee, Theresa ; Rajasekaran, Narendiran
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A522-A526
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ArticlesPeer ReviewedFull Text
Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
Author / Creator:Mai, Hai-Qiang ; Chen, Qiu-Yan ; Chen, Dongping ; Hu, Chaosu ; Yang, Kunyu ; Wen, Jiyu ; Li, Jingao ; Shi, Ying-Rui ; Jin, Feng ; Xu, Ruilian ; Pan, Jianji ; Qu, Shenhong ; Li, Ping ; Hu, Chunhong ; Liu, Yi-Chun ; Jiang, Yi ; He, Xia ; Wang, Hung-Ming ; Lim, Wan-Teck ; Liao, Wangjun ; He, Xiaohui ; Chen, Xiaozhong ; Liu, Zhigang ; Yuan, Xianglin ; Li, Qi ; Lin, Xiaoyan ; Jing, Shanghua ; Chen, Yanju ; Lu, Yin ; Hsieh, Ching-Yun ; Yang, Muh-Hwa ; Yen, Chia-Jui ; Samol, Jens ; Feng, Hui ; Yao, Sheng ; Keegan, Patricia ; Xu, Rui-Hua
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-09, Vol.27 (9), p.1536-1543
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ArticlesPeer ReviewedFull Text
Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis
Author / Creator:Beaver, Julia A ; Hazarika, Maitreyee ; Mulkey, Flora ; Mushti, Sirisha ; Chen, Huanyu ; He, Kun ; Sridhara, Rajeshwari ; Goldberg, Kirsten B ; Chuk, Meredith K ; Chi, Dow-Chung ; Chang, Jennie ; Barone, Amy ; Balasubramaniam, Sanjeeve ; Blumenthal, Gideon M ; Keegan, Patricia ; Pazdur, Richard ; Theoret, Marc R
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-02, Vol.19 (2), p.229-239
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ArticlesPeer ReviewedFull Text
Toripalimab plus nab-paclitaxel in metastatic or recurrent triple-negative breast cancer: a randomized phase 3 trial
Author / Creator:Jiang, Zefei ; Ouyang, Quchang ; Sun, Tao ; Zhang, Qingyuan ; Teng, Yuee ; Cui, Jiuwei ; Wang, Haibo ; Yin, Yongmei ; Wang, Xiaojia ; Zhou, Xin ; Wang, Yongsheng ; Sun, Gang ; Wang, Jingfen ; Zhang, Lili ; Yang, Jin ; Qian, Jun ; Yan, Min ; Liu, Xinlan ; Yi, Tienan ; Cheng, Ying ; Li, Man ; Zang, Aimin ; Wang, Shusen ; Wang, Chuan ; Wu, Xinhong ; Cheng, Jing ; Li, Hui ; Lin, Ying ; Geng, Cuizhi ; Gu, Kangsheng ; Xie, Chunwei ; Xiong, Huihua ; Wu, Xiaohong ; Yang, Junlan ; Li, Qingshan ; Chen, Yiding ; Li, Fanfan ; Zhang, Anqin ; Zhang, Yongqiang ; Wu, Yudong ; Nie, Jianyun ; Liu, Qiang ; Wang, Kun ; Mo, Xueli ; Chen, Lilin ; Pan, Yueyin ; Fu, Peifen ; Zhang, Helong ; Pang, Danmei ; Sheng, Yuan ; Han, Yunwei ; Wang, Hongxia ; Cang, Shundong ; Luo, Xianming ; Yu, Wenbo ; Deng, Rong ; Yang, Chaoqiang ; Keegan, Patricia
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2024-01, Vol.30 (1), p.249-256
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ArticlesPeer ReviewedFull Text
The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention
Author / Creator:Theoret, Marc R ; Ning, Yang-Min ; Zhang, Jenny J ; Justice, Robert ; Keegan, Patricia ; Pazdur, Richard
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2011-07, Vol.365 (2), p.97-99
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ArticlesPeer ReviewedFull Text
Time dependent pharmacokinetics of pembrolizumab in patients with solid tumor and its correlation with best overall response
Author / Creator:Li, Hongshan ; Yu, Jingyu ; Liu, Chao ; Liu, Jiang ; Subramaniam, Sriram ; Zhao, Hong ; Blumenthal, Gideon M. ; Turner, David C. ; Li, Claire ; Ahamadi, Malidi ; de Greef, Rik ; Chatterjee, Manash ; Kondic, Anna G. ; Stone, Julie A. ; Booth, Brian P. ; Keegan, Patricia ; Rahman, Atiqur ; Wang, Yaning
Publisher:New York: Springer US
Journal title:Journal of pharmacokinetics and pharmacodynamics, 2017-10, Vol.44 (5), p.403-414
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ArticlesPeer ReviewedFull Text
Toripalimab, a therapeutic monoclonal anti-PD-1 antibody with high binding affinity to PD-1 and enhanced potency to activate human T cells
Author / Creator:Rajasekaran, Narendiran ; Wang, Xiaoguang ; Ravindranathan, Sruthi ; Chin, Daniel J ; Tseng, Su-Yi ; Klakamp, Scott L ; Widmann, Kate ; Kapoor, Varun N ; Vexler, Vladimir ; Keegan, Patricia ; Yao, Sheng ; LaVallee, Theresa ; Khare, Sanjay D
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2024-02, Vol.73 (3), p.60-60, Article 60
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Newspaper ArticlesFull Text
Whose America Belongs in Public School?
Author / Creator:Marriott, Michel
Publisher:New York, N.Y: New York Times Company
Journal title:The New York times, 1991-06-23
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ArticlesPeer ReviewedFull Text
Anti-PD-1 antibody treatment for melanoma – Authors' reply
Author / Creator:Beaver, Julia A ; Keegan, Patricia ; Lemery, Steven ; Pazdur, Richard ; Theoret, Marc R
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-05, Vol.19 (5), p.e220-e220
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ArticlesPeer ReviewedFull Text
Immune Response Evaluation and Treatment with Immune Checkpoint Inhibitors Beyond Clinical Progression: Response Assessments for Cancer Immunotherapy
Author / Creator:Mushti, Sirisha L. ; Mulkey, Flora ; Tang, Shenghui ; Singh, Harpreet ; Lemery, Steven J. ; Goldberg, Kirsten B. ; Sridhara, Rajeshwari ; Keegan, Patricia ; Kluetz, Paul G. ; Pazdur, Richard ; Theoret, Marc R. ; Beaver, Julia A.
Publisher:New York: Springer US
Journal title:Current oncology reports, 2020-11, Vol.22 (11), p.116-116, Article 116
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ArticlesPeer ReviewedFull Text
Publisher Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial
Author / Creator:Mai, Hai-Qiang ; Chen, Qiu-Yan ; Chen, Dongping ; Hu, Chaosu ; Yang, Kunyu ; Wen, Jiyu ; Li, Jingao ; Shi, Ying-Rui ; Jin, Feng ; Xu, Ruilian ; Pan, Jianji ; Qu, Shenhong ; Li, Ping ; Hu, Chunhong ; Liu, Yi-Chun ; Jiang, Yi ; He, Xia ; Wang, Hung-Ming ; Lim, Wan-Teck ; Liao, Wangjun ; He, Xiaohui ; Chen, Xiaozhong ; Liu, Zhigang ; Yuan, Xianglin ; Li, Qi ; Lin, Xiaoyan ; Jing, Shanghua ; Chen, Yanju ; Lu, Yin ; Hsieh, Ching-Yun ; Yang, Muh-Hwa ; Yen, Chia-Jui ; Samol, Jens ; Feng, Hui ; Yao, Sheng ; Keegan, Patricia ; Xu, Rui-Hua
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2022-01, Vol.28 (1), p.214-214
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ArticlesPeer ReviewedFull Text
An FDA Pooled Analysis of Patients with Melanoma Treated with an Anti-PD1 Antibody Beyond RECIST Progression
Author / Creator:Beaver, Julia A. ; Hazarika, Maitreyee ; Mulkey, Flora ; Mushti, Sirisha ; Chen, Huanyu ; He, Kun ; Sridhara, Rajeshwari ; Goldberg, Kirsten B. ; Chuk, Meredith K. ; Chi, Dow-Chung ; Chang, Jennie ; Barone, Amy ; Balasubramaniam, Sanjeeve ; Blumenthal, Gideon M. ; Keegan, Patricia ; Pazdur, Richard ; Theoret, Marc R.
Journal title:The lancet oncology, 2018-01, Vol.19 (2), p.229-239
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ArticlesPeer ReviewedFull Text
Evaluation of Blinded Independent Central Review of Tumor Progression in Oncology Clinical Trials: A Meta-analysis
Author / Creator:Zhang, Jenny J. ; Chen, Huanyu ; He, Kun ; Tang, Shenghui ; Justice, Robert ; Keegan, Patricia ; Pazdur, Richard ; Sridhara, Rajeshwari
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Therapeutic Innovation & Regulatory Science, 2013-03, Vol.47 (2), p.167-174
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ArticlesPeer ReviewedFull Text
CMR to stratify post-TAVR paravalvular leak in patients with suboptimal echocardiography
Author / Creator:Hartlage, Gregory ; Hayek, Salim ; Babaliaros, Vasilis ; Keegan, Patricia ; Thourani, Vinod ; Lerakis, Stamatios
Publisher:BioMed Central Ltd
Journal title:Journal of cardiovascular magnetic resonance, 2014-01, Vol.16 (Suppl 1), p.O102-O102, Article O102
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ArticlesPeer ReviewedFull Text
Development and regulation of monoclonal antibody products: challenges and opportunities
Author / Creator:Weinberg, Wendy C ; Frazier-Jessen, Michelle R ; Wu, Wen Jin ; Weir, Andrea ; Hartsough, Melanie ; Keegan, Patricia ; Fuchs, Chana
Publisher:Netherlands: Springer Nature B.V
Journal title:Cancer and metastasis reviews, 2005-12, Vol.24 (4), p.569-584
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Showing 1 to 20 of 43 results

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First FDA Approval Agnostic of Cancer Site — When a Biomarker Defines the Indication

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FDA Supplemental Approval Summary: Lenvatinib for the Treatment of Unresectable Hepatocellular Carcinoma

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KEEGAN, Patricia G

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Systematic Review of PD‐1/PD‐L1 Inhibitors in Oncology: From Personalized Medicine to Public Health

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Comparison of iRECIST versus RECIST V.1.1 in patients treated with an anti-PD-1 or PD-L1 antibody: pooled FDA analysis

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468 Characteristics of toripalimab: a next generation anti-PD-1 antibody with potent T cell activation and enhanced clinical efficacy irrespective of PD-L-1 status

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Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial

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Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis

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Toripalimab plus nab-paclitaxel in metastatic or recurrent triple-negative breast cancer: a randomized phase 3 trial

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The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention

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Time dependent pharmacokinetics of pembrolizumab in patients with solid tumor and its correlation with best overall response

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Toripalimab, a therapeutic monoclonal anti-PD-1 antibody with high binding affinity to PD-1 and enhanced potency to activate human T cells

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Whose America Belongs in Public School?

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Anti-PD-1 antibody treatment for melanoma – Authors' reply

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Immune Response Evaluation and Treatment with Immune Checkpoint Inhibitors Beyond Clinical Progression: Response Assessments for Cancer Immunotherapy

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Publisher Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial

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An FDA Pooled Analysis of Patients with Melanoma Treated with an Anti-PD1 Antibody Beyond RECIST Progression

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Evaluation of Blinded Independent Central Review of Tumor Progression in Oncology Clinical Trials: A Meta-analysis

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CMR to stratify post-TAVR paravalvular leak in patients with suboptimal echocardiography

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Development and regulation of monoclonal antibody products: challenges and opportunities

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