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NOP receptor pharmacological profile - A dynamic mass redistribution study

NOP receptor pharmacological profile - A dynamic mass redistribution study

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be7ca1bc72664702915490507d966f61

NOP receptor pharmacological profile - A dynamic mass redistribution study

About this item

Full title

NOP receptor pharmacological profile - A dynamic mass redistribution study

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-08, Vol.13 (8), p.e0203021-e0203021

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (Gi/o) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents. The label free dynamic mass redistribution (DMR) approach has been demonstrated useful fo...

Alternative Titles

Full title

NOP receptor pharmacological profile - A dynamic mass redistribution study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_be7ca1bc72664702915490507d966f61

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_be7ca1bc72664702915490507d966f61

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0203021

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