Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repr...
Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Thymic T cell development and T cell receptor repertoire selection are dependent on essential molecular cues provided by thymic epithelial cells (TEC). TEC development and function are regulated by their epigenetic landscape, in which the repressive H3K27me3 epigenetic marks are catalyzed by polycomb repressive complex 2 (PRC2). Here we show that a...
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Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2
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TN_cdi_doaj_primary_oai_doaj_org_article_bea5fbe30e2340e383f4864410b7a2fd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bea5fbe30e2340e383f4864410b7a2fd
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24158-w