Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial...
Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease
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Author / Creator
Siddiqui, Tohid , Cosacak, Mehmet Ilyas , Popova, Stanislava , Bhattarai, Prabesh , Yilmaz, Elanur , Lee, Annie J. , Min, Yuhao , Wang, Xue , Allen, Mariet , İş, Özkan , Atasavum, Zeynep Tansu , Rodriguez-Muela, Natalia , Vardarajan, Badri N. , Flaherty, Delaney , Teich, Andrew F. , Santa-Maria, Ismael , Freudenberg, Uwe , Werner, Carsten , Tosto, Giuseppe , Mayeux, Richard , Ertekin-Taner, Nilüfer and Kizil, Caghan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Neurogenesis, crucial for brain resilience, is reduced in Alzheimer’s disease (AD) that induces astroglial reactivity at the expense of the pro-neurogenic potential, and restoring neurogenesis could counteract neurodegenerative pathology. However, the molecular mechanisms promoting pro-neurogenic astroglial fate despite AD pathology are unknown. In...
Alternative Titles
Full title
Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Cosacak, Mehmet Ilyas
Popova, Stanislava
Bhattarai, Prabesh
Yilmaz, Elanur
Lee, Annie J.
Min, Yuhao
Wang, Xue
Allen, Mariet
İş, Özkan
Atasavum, Zeynep Tansu
Rodriguez-Muela, Natalia
Vardarajan, Badri N.
Flaherty, Delaney
Teich, Andrew F.
Santa-Maria, Ismael
Freudenberg, Uwe
Werner, Carsten
Tosto, Giuseppe
Mayeux, Richard
Ertekin-Taner, Nilüfer
Kizil, Caghan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bebfc2431c024aae887659ececd580cc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bebfc2431c024aae887659ececd580cc
Other Identifiers
ISSN
2057-3995
E-ISSN
2057-3995
DOI
10.1038/s41536-023-00311-5