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Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial...

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bebfc2431c024aae887659ececd580cc

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease

About this item

Full title

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease

Publisher

London: Nature Publishing Group UK

Journal title

npj Regenerative medicine, 2023-07, Vol.8 (1), p.33-33, Article 33

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neurogenesis, crucial for brain resilience, is reduced in Alzheimer’s disease (AD) that induces astroglial reactivity at the expense of the pro-neurogenic potential, and restoring neurogenesis could counteract neurodegenerative pathology. However, the molecular mechanisms promoting pro-neurogenic astroglial fate despite AD pathology are unknown. In...

Alternative Titles

Full title

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_bebfc2431c024aae887659ececd580cc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bebfc2431c024aae887659ececd580cc

Other Identifiers

ISSN

2057-3995

E-ISSN

2057-3995

DOI

10.1038/s41536-023-00311-5

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