Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary seq...
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Uncovering mechanisms of epigenome evolution is an essential step towards understanding the evolution of different cellular phenotypes. While studies have confirmed DNA methylation as a conserved epigenetic mechanism in mammalian development, little is known about the conservation of tissue-specific genome-wide DNA methylation patterns.
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Full title
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
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TN_cdi_doaj_primary_oai_doaj_org_article_bed260852cb4434482217c71d676d779
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bed260852cb4434482217c71d676d779
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-017-4115-6
