Genetic risk factors underlying white matter hyperintensities and cortical atrophy
Genetic risk factors underlying white matter hyperintensities and cortical atrophy
About this item
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Author / Creator
Patel, Yash , Shin, Jean , Sliz, Eeva , Tang, Ariana , Mishra, Aniket , Xia, Rui , Hofer, Edith , Rajula, Hema Sekhar Reddy , Wang, Ruiqi , Beyer, Frauke , Horn, Katrin , Riedl, Max , Yu, Jing , Völzke, Henry , Bülow, Robin , Völker, Uwe , Frenzel, Stefan , Wittfeld, Katharina , Van der Auwera, Sandra , Mosley, Thomas H. , Bouteloup, Vincent , Lambert, Jean-Charles , Chêne, Geneviève , Dufouil, Carole , Tzourio, Christophe , Mangin, Jean-François , Gottesman, Rebecca F. , Fornage, Myriam , Schmidt, Reinhold , Yang, Qiong , Witte, Veronica , Scholz, Markus , Loeffler, Markus , Roshchupkin, Gennady V. , Ikram, M. Arfan , Grabe, Hans J. , Seshadri, Sudha , Debette, Stephanie , Paus, Tomas and Pausova, Zdenka
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
White matter hyperintensities index structural abnormalities in the cerebral white matter, including axonal damage. The latter may promote atrophy of the cerebral cortex, a key feature of dementia. Here, we report a study of 51,065 individuals from 10 cohorts demonstrating that higher white matter hyperintensity volume associates with lower cortica...
Alternative Titles
Full title
Genetic risk factors underlying white matter hyperintensities and cortical atrophy
Authors, Artists and Contributors
Author / Creator
Shin, Jean
Sliz, Eeva
Tang, Ariana
Mishra, Aniket
Xia, Rui
Hofer, Edith
Rajula, Hema Sekhar Reddy
Wang, Ruiqi
Beyer, Frauke
Horn, Katrin
Riedl, Max
Yu, Jing
Völzke, Henry
Bülow, Robin
Völker, Uwe
Frenzel, Stefan
Wittfeld, Katharina
Van der Auwera, Sandra
Mosley, Thomas H.
Bouteloup, Vincent
Lambert, Jean-Charles
Chêne, Geneviève
Dufouil, Carole
Tzourio, Christophe
Mangin, Jean-François
Gottesman, Rebecca F.
Fornage, Myriam
Schmidt, Reinhold
Yang, Qiong
Witte, Veronica
Scholz, Markus
Loeffler, Markus
Roshchupkin, Gennady V.
Ikram, M. Arfan
Grabe, Hans J.
Seshadri, Sudha
Debette, Stephanie
Paus, Tomas
Pausova, Zdenka
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_bf9509bdebd5484ea27088d73ad6ccb8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_bf9509bdebd5484ea27088d73ad6ccb8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53689-1
