Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination...
Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI
About this item
Full title
Author / Creator
Kim, Yonghyo , Sugihara, Yutaka , Kim, Tae Young , Cho, Sung Min , Kim, Jin Young , Lee, Ju Yeon , Yoo, Jong Shin , Song, Doona , Han, Gyoonhee , Rezeli, Melinda , Welinder, Charlotte , Appelqvist, Roger , Marko-Varga, György , Kwon, Ho Jeong , Övriga starka forskningsmiljöer , LUCC: Lund University Cancer Centre , Section I , Department of Biomedical Engineering , Lunds Tekniska Högskola , Departments at LTH , Department of Clinical Sciences, Lund , Faculty of Engineering, LTH , Lund University , Sektion V , Section V , Profile areas and other strong research environments , Tumor microenvironment , Institutioner vid LTH , Institutionen för biomedicinsk teknik , Faculty of Medicine , Medicinska fakulteten , Mass Spectrometry , Avdelningen för biomedicinsk teknik , Other Strong Research Environments , Institutionen för kliniska vetenskaper, Lund , Lunds universitet , Sektion I , Masspektrometri , Tumörmikromiljö , Profilområden och andra starka forskningsmiljöer , Division for Biomedical Engineering , Clinical Protein Science and Imaging and LUCC: Lunds universitets cancercentrum
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
Although natural products are an important source of drugs and drug leads, identification and validation of their target proteins have proven difficult. Here, we report the development of a systematic strategy for target identification and validation employing drug affinity responsive target stability (DARTS) and mass spectrometry imaging (MSI) wit...
Alternative Titles
Full title
Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI
Authors, Artists and Contributors
Author / Creator
Sugihara, Yutaka
Kim, Tae Young
Cho, Sung Min
Kim, Jin Young
Lee, Ju Yeon
Yoo, Jong Shin
Song, Doona
Han, Gyoonhee
Rezeli, Melinda
Welinder, Charlotte
Appelqvist, Roger
Marko-Varga, György
Kwon, Ho Jeong
Övriga starka forskningsmiljöer
LUCC: Lund University Cancer Centre
Section I
Department of Biomedical Engineering
Lunds Tekniska Högskola
Departments at LTH
Department of Clinical Sciences, Lund
Faculty of Engineering, LTH
Lund University
Sektion V
Section V
Profile areas and other strong research environments
Tumor microenvironment
Institutioner vid LTH
Institutionen för biomedicinsk teknik
Faculty of Medicine
Medicinska fakulteten
Mass Spectrometry
Avdelningen för biomedicinsk teknik
Other Strong Research Environments
Institutionen för kliniska vetenskaper, Lund
Lunds universitet
Sektion I
Masspektrometri
Tumörmikromiljö
Profilområden och andra starka forskningsmiljöer
Division for Biomedical Engineering
Clinical Protein Science and Imaging
LUCC: Lunds universitets cancercentrum
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c0c1eaf16c404d448dab81d12e8deefa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c0c1eaf16c404d448dab81d12e8deefa
Other Identifiers
ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom10040508
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