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Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway
Author / Creator:Lee, Minji ; Kim, Jong Hyun ; Yoon, Ina ; Lee, Chulho ; Sichani, Mohammad Fallahi ; Kang, Jong Soon ; Kang, Jeonghyun ; Guo, Min ; Lee, Kang Young ; Han, Gyoonhee ; Kim, Sunghoon ; Han, Jung Min
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (23), p.E5279-E5288
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Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer
Author / Creator:Hwang, Won Chan ; Song, Doona ; Lee, Hyesung ; Oh, Changmok ; Lim, Seong Hun ; Bae, Hyeon Jeong ; Kim, Nam Doo ; Han, Gyoonhee ; Min, Do Sik
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2022, 54(0), , pp.1-14
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Euodia daniellii Hemsl. Extract and Its Active Component Hesperidin Accelerate Cutaneous Wound Healing via Activation of Wnt/β-Catenin Signaling Pathway
Author / Creator:Yoon, Minguen ; Seo, Seol Hwa ; Choi, Seonghwi ; Han, Gyoonhee ; Choi, Kang-Yell
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-10, Vol.27 (20), p.7134
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Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction
Author / Creator:Kim, Jong Hyun ; Lee, Chulho ; Lee, Minji ; Wang, Haipeng ; Kim, Kibum ; Park, Seung Joon ; Yoon, Ina ; Jang, Jayun ; Zhao, Hanchao ; Kim, Hoi Kyoung ; Kwon, Nam Hoon ; Jeong, Seung Jae ; Yoo, Hee Chan ; Kim, Jae Hyun ; Yang, Jee Sun ; Lee, Myeong Youl ; Lee, Chang Woo ; Yun, Jieun ; Oh, Soo Jin ; Kang, Jong Soon ; Martinis, Susan A. ; Hwang, Kwang Yeon ; Guo, Min ; Han, Gyoonhee ; Han, Jung Min ; Kim, Sunghoon
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.732-15, Article 732
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Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration
Author / Creator:Son, Kook ; You, Jae-Sung ; Yoon, Mee-Sup ; Dai, Chong ; Kim, Jong Hyun ; Khanna, Nidhi ; Banerjee, Aditi ; Martinis, Susan A ; Han, Gyoonhee ; Han, Jung Min ; Kim, Sunghoon ; Chen, Jie
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-05, Vol.129 (5), p.2088-2093
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AB5-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus
Author / Creator:Ahn, Jina ; Yu, Ji Eun ; Kim, Hanna ; Sung, Jemin ; Han, Gyoonhee ; Sohn, Myung Hyun ; Seong, Baik-Lin
Publisher:Basel: MDPI AG
Journal title:Toxins, 2023-06, Vol.15 (7), p.425
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A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer
Author / Creator:Park, Jieun ; Cho, Yong-Hee ; Shin, Wook-Jin ; Lee, Sang-Kyu ; Lee, JaeHeon ; Kim, Taehyung ; Cha, Pu-Hyeon ; Yang, Jee Sun ; Cho, Jaebeom ; Min, Do Sik ; Han, Gyoonhee ; Lee, Ho-Young ; Choi, Kang-Yell
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-01, Vol.9 (1), p.648-648, Article 648
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PRMT5 promotes DNA repair through methylation of 53BP1 and is regulated by Src-mediated phosphorylation
Author / Creator:Hwang, Jee Won ; Kim, Su-Nam ; Myung, Nayeon ; Song, Doona ; Han, Gyoonhee ; Bae, Gyu-Un ; Bedford, Mark T. ; Kim, Yong Kee
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2020-08, Vol.3 (1), p.428, Article 428
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Glycosylation of Hemagglutinin and Neuraminidase of Influenza A Virus as Signature for Ecological Spillover and Adaptation among Influenza Reservoirs
Author / Creator:Kim, Paul ; Jang, Yo Han ; Kwon, Soon Bin ; Lee, Chung Min ; Han, Gyoonhee ; Seong, Baik Lin
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2018-04, Vol.10 (4), p.183
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Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer
Author / Creator:Kim, Eun Young ; Lee, Jin Gu ; Lee, Jung Mo ; Kim, Arum ; Yoo, Hee Chan ; Kim, Kibum ; Lee, Minji ; Lee, Chulho ; Han, Gyoonhee ; Han, Jung Min ; Chang, Yoon Soo
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2019-05, Vol.11, p.1758835919846798-1758835919846798
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Simultaneous Suppression of Multiple Programmed Cell Death Pathways by miRNA-105 in Cardiac Ischemic Injury
Author / Creator:Shin, Sunhye ; Choi, Jung-Won ; Moon, Hanbyeol ; Lee, Chang Youn ; Park, Jun-Hee ; Lee, Jiyun ; Seo, Hyang-Hee ; Han, Gyoonhee ; Lim, Soyeon ; Lee, Seahyoung ; Kim, Sang Woo ; Hwang, Ki-Chul
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2019-03, Vol.14, p.438-449
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Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2
Author / Creator:Moon, Hanbyeol ; Choi, Jung-Won ; Song, Byeong-Wook ; Kim, Il-Kwon ; Lim, Soyeon ; Lee, Seahyoung ; Han, Gyoonhee ; Hwang, Ki-Chul ; Kim, Sang Woo
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-02, Vol.11 (3), p.567
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Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
Author / Creator:Ryu, Yeong Chan ; Kim, You-Rin ; Park, Jiyeon ; Choi, Sehee ; Ryu, Won-Ji ; Kim, Geon-Uk ; Kim, Eunhwan ; Hwang, Yumi ; Kim, Heejene ; Han, Gyoonhee ; Lee, Soung-Hoon ; Choi, Kang-Yell
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2022-12, Vol.14 (12), p.2774
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A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab
Author / Creator:Lee, Sang-Kyu ; Cho, Yong-Hee ; Cha, Pu-Hyeon ; Yoon, Jeong-Soo ; Ro, Eun Ji ; Jeong, Woo-Jeong ; Park, Jieun ; Kim, Hyuntae ; Il Kim, Tae ; Min, Do Sik ; Han, Gyoonhee ; Choi, Kang-Yell
Publisher:London: Nature Publishing Group UK
Journal title:Experimental and Molecular Medicine, 2018, 50(0), , pp.1-12
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Chemical inhibition of prometastatic lysyl-tRNA synthetase–laminin receptor interaction
Author / Creator:Kim, Dae Gyu ; Lee, Jin Young ; Kwon, Nam Hoon ; Fang, Pengfei ; Zhang, Qian ; Wang, Jing ; Young, Nicolas L ; Guo, Min ; Cho, Hye Young ; Mushtaq, Ameeq Ul ; Jeon, Young Ho ; Choi, Jin Woo ; Han, Jung Min ; Kang, Ho Woong ; Joo, Jae Eun ; Hur, Youn ; Kang, Wonyoung ; Yang, Heekyoung ; Nam, Do-Hyun ; Lee, Mi-Sook ; Lee, Jung Weon ; Kim, Eun-Sook ; Moon, Aree ; Kim, Kibom ; Kim, Doyeun ; Kang, Eun Joo ; Moon, Youngji ; Rhee, Kyung Hee ; Han, Byung Woo ; Yang, Jee Sun ; Han, Gyoonhee ; Yang, Won Suk ; Lee, Cheolju ; Wang, Ming-Wei ; Kim, Sunghoon
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2014-01, Vol.10 (1), p.29-34
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Chemopreventive and chemotherapeutic effect of a novel histone deacetylase inhibitor, by specificity protein 1 in MDA-MB-231 human breast cancer cells
Author / Creator:Shin, Ji-Ae ; Han, Gyoonhee ; Kim, Hyun-Jung ; Kim, Hwan-Mook ; Cho, Sung-Dae
Publisher:Hagerstown, MD: Lippincott Williams & Wilkins, a business of Wolters Kluwer Health
Journal title:European journal of cancer prevention, 2014-07, Vol.23 (4), p.277-285
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Investigation of memory-enhancing botanical mixture and their isolated compounds for inhibition of amyloid-β and tau aggregation
Author / Creator:Baek, Seungyeop ; Park, Sohui ; Shin, Jisu ; Lee, Jun-Seok ; Kim, Hye Yun ; Han, Gyoonhee ; Kim, YoungSoo
Publisher:Singapore: Springer Nature Singapore
Journal title:Applied Biological Chemistry, 2020, 63(3), , pp.1-7
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CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
Author / Creator:Ryu, Yeong Chan ; Park, Jiyeon ; Kim, You-Rin ; Choi, Sehee ; Kim, Geon-Uk ; Kim, Eunhwan ; Hwang, Yumi ; Kim, Heejene ; Han, Gyoonhee ; Lee, Soung-Hoon ; Choi, Kang-Yell
Publisher:Basel: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.555
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A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS-mediated c-Abl/p38 MAPK signaling
Author / Creator:Chung, Kyung-Sook ; Han, Gyoonhee ; Kim, Bo-Kyung ; Kim, Hwan-Mook ; Yang, Jee Sun ; Ahn, Jiwon ; Lee, Kyeong ; Song, Kyung-Bin ; Won, Misun
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2013-12, Vol.72 (6), p.1315-1324
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Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI
Author / Creator:Kim, Yonghyo ; Sugihara, Yutaka ; Kim, Tae Young ; Cho, Sung Min ; Kim, Jin Young ; Lee, Ju Yeon ; Yoo, Jong Shin ; Song, Doona ; Han, Gyoonhee ; Rezeli, Melinda ; Welinder, Charlotte ; Appelqvist, Roger ; Marko-Varga, György ; Kwon, Ho Jeong
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2020-03, Vol.10 (4), p.508
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Showing 1 to 20 of 35 results

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Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway

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Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer

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Euodia daniellii Hemsl. Extract and Its Active Component Hesperidin Accelerate Cutaneous Wound Healing via Activation of Wnt/β-Catenin Signaling Pathway

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Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction

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Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration

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AB5-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus

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A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer

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PRMT5 promotes DNA repair through methylation of 53BP1 and is regulated by Src-mediated phosphorylation

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Glycosylation of Hemagglutinin and Neuraminidase of Influenza A Virus as Signature for Ecological Spillover and Adaptation among Influenza Reservoirs

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Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer

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Simultaneous Suppression of Multiple Programmed Cell Death Pathways by miRNA-105 in Cardiac Ischemic Injury

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Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2

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Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling

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A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab

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Chemical inhibition of prometastatic lysyl-tRNA synthetase–laminin receptor interaction

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Chemopreventive and chemotherapeutic effect of a novel histone deacetylase inhibitor, by specificity protein 1 in MDA-MB-231 human breast cancer cells

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Investigation of memory-enhancing botanical mixture and their isolated compounds for inhibition of amyloid-β and tau aggregation

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CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2

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A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS-mediated c-Abl/p38 MAPK signaling

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Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI

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