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Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages

Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c0d3184f75cd44758488f01fcfbdc0be

Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages

About this item

Full title

Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages

Publisher

Switzerland: MDPI AG

Journal title

Pharmaceutics, 2020-11, Vol.12 (12), p.1138

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic macrophages efficiently capture particulate antigens from the blood and transfer t...

Alternative Titles

Full title

Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c0d3184f75cd44758488f01fcfbdc0be

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c0d3184f75cd44758488f01fcfbdc0be

Other Identifiers

ISSN

1999-4923

E-ISSN

1999-4923

DOI

10.3390/pharmaceutics12121138

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