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ArticlesPeer ReviewedFull Text
Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes
Author / Creator:Affandi, Alsya J. ; Grabowska, Joanna ; Olesek, Katarzyna ; Venegas, Miguel Lopez ; Barbaria, Arnaud ; Rodríguez, Ernesto ; Mulder, Patrick P. G. ; Pijffers, Helen J. ; Ambrosini, Martino ; Kalay, Hakan ; O’Toole, Tom ; Zwart, Eline S. ; Kazemier, Geert ; Nazmi, Kamran ; Bikker, Floris J. ; Stöckl, Johannes ; van den Eertwegh, Alfons J. M. ; de Gruijl, Tanja D. ; Storm, Gert ; van Kooyk, Yvette ; den Haan, Joke M. M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (44), p.27528-27539
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Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells
Author / Creator:Perdicchio, Maurizio ; Ilarregui, Juan M. ; Verstege, Marleen I. ; Cornelissen, Lenneke A. M. ; Schetters, Sjoerd T. T. ; Engels, Steef ; Ambrosini, Martino ; Kalay, Hakan ; Veninga, Henrike ; den Haan, Joke M. M. ; van Berkel, Lisette A. ; Samsom, Janneke N. ; Crocker, Paul R. ; Sparwasser, Tim ; Berod, Luciana ; Garcia-Vallejo, Juan J. ; van Kooyk, Yvette ; Unger, Wendy W. J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (12), p.3329-3334
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Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells
Author / Creator:Fehres, Cynthia M ; Duinkerken, Sanne ; Bruijns, Sven CM ; Kalay, Hakan ; van Vliet, Sandra J ; Ambrosini, Martino ; de Gruijl, Tanja D ; Unger, Wendy WJ ; Garcia-Vallejo, Juan J ; van Kooyk, Yvette
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2017-04, Vol.14 (4), p.360-370
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Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation
Author / Creator:Ilarregui, Juan M ; Kooij, Gijs ; Rodríguez, Ernesto ; van der Pol, Susanne M A ; Koning, Nathalie ; Kalay, Hakan ; van der Horst, Joost C ; van Vliet, Sandra J ; García-Vallejo, Juan J ; de Vries, Helga E ; van Kooyk, Yvette
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2019-06, Vol.16 (1), p.130-130, Article 130
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Glycan modification of antigen alters its intracellular routing in dendritic cells, promoting priming of T cells
Author / Creator:Streng-Ouwehand, Ingeborg ; Ho, Nataschja I ; Litjens, Manja ; Kalay, Hakan ; Boks, Martine Annemarie ; Cornelissen, Lenneke A M ; Kaur Singh, Satwinder ; Saeland, Eirikur ; Garcia-Vallejo, Juan J ; Ossendorp, Ferry A ; Unger, Wendy W J ; van Kooyk, Yvette
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2016-03, Vol.5
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Vaccination with DC-SIGN-Targeting αGC Liposomes Leads to Tumor Control, Irrespective of Suboptimally Activated T-Cells
Author / Creator:de Haas, Aram M ; Stolk, Dorian A ; Schetters, Sjoerd T T ; Goossens-Kruijssen, Laura ; Keuning, Eelco ; Ambrosini, Martino ; Boon, Louis ; Kalay, Hakan ; Storm, Gert ; van der Vliet, Hans J ; de Gruijl, Tanja D ; van Kooyk, Yvette
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2024-05, Vol.16 (5), p.581
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Optimization of Liposomes for Antigen Targeting to Splenic CD169 + Macrophages
Author / Creator:Nijen Twilhaar, Maarten K ; Czentner, Lucas ; Grabowska, Joanna ; Affandi, Alsya J ; Lau, Chun Yin Jerry ; Olesek, Katarzyna ; Kalay, Hakan ; van Nostrum, Cornelus F ; van Kooyk, Yvette ; Storm, Gert ; Haan, Joke M M den
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2020-11, Vol.12 (12), p.1138
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Phenotypic and Functional Properties of Human Steady State CD14+ and CD1a+ Antigen Presenting Cells and Epidermal Langerhans Cells
Author / Creator:Fehres, Cynthia M ; Bruijns, Sven C M ; Sotthewes, Brigit N ; Kalay, Hakan ; Schaffer, Lana ; Head, Steven R ; de Gruijl, Tanja D ; Garcia-Vallejo, Juan J ; van Kooyk, Yvette
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-11, Vol.10 (11), p.e0143519-e0143519
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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets
Author / Creator:Duinkerken, Sanne ; Horrevorts, Sophie K. ; Kalay, Hakan ; Ambrosini, Martino ; Rutte, Lisa ; de Gruijl, Tanja D. ; Garcia-Vallejo, Juan J. ; van Kooyk, Yvette
Journal title:Theranostics, 2019, Vol.9 (20), p.5797-5809
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ArticlesPeer ReviewedFull Text
849 Optimization of a GM3-containing liposomal vaccine that delivers antigen to CD169+ splenic macrophages
Author / Creator:Twilhaar, Maarten Nijen ; Colomo, Lucas Czentner ; Grabowska, Joanna ; Affandi, Alsya ; Olesek, Katarina ; Kalay, Hakan ; Nostrum, Rene van ; Crocker, Paul ; Kooyk, Yvette van ; Storm, Gert ; Haan, Joke den
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A506-A506
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ArticlesPeer ReviewedFull Text
Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets
Author / Creator:Duinkerken, Sanne ; Horrevorts, Sophie K ; Kalay, Hakan ; Ambrosini, Martino ; Rutte, Lisa ; de Gruijl, Tanja D ; Garcia-Vallejo, Juan J ; van Kooyk, Yvette
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2019-01, Vol.9 (20), p.5797-5809
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ArticlesPeer ReviewedFull Text
Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy
Author / Creator:Rodríguez, Ernesto ; Kalay, Hakan ; Noya, Verónica ; Brossard, Natalie ; Giacomini, Cecilia ; van Kooyk, Yvette ; García-Vallejo, Juan J. ; Freire, Teresa
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.46748-46748, Article 46748
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In situ Delivery of Tumor Antigen– and Adjuvant-Loaded Liposomes Boosts Antigen-Specific T-Cell Responses by Human Dermal Dendritic Cells
Author / Creator:Boks, Martine A. ; Bruijns, Sven C.M. ; Ambrosini, Martino ; Kalay, Hakan ; van Bloois, Louis ; Storm, Gert ; Gruijl, Tanja de ; van Kooyk, Yvette
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2015-11, Vol.135 (11), p.2697-2704
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In situ Delivery of Antigen to DC-SIGN+CD14+ Dermal Dendritic Cells Results in Enhanced CD8+ T-Cell Responses
Author / Creator:Fehres, Cynthia M. ; van Beelen, Astrid J. ; Bruijns, Sven C.M. ; Ambrosini, Martino ; Kalay, Hakan ; Bloois, Louis van ; Unger, Wendy W.J. ; Garcia-Vallejo, Juan J. ; Storm, Gert ; de Gruijl, Tanja D. ; Kooyk, Yvette van
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2015-09, Vol.135 (9), p.2228-2236
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Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans
Author / Creator:van Dinther, Dieke ; Lopez Venegas, Miguel ; Veninga, Henrike ; Olesek, Katarzyna ; Hoogterp, Leoni ; Revet, Mirjam ; Ambrosini, Martino ; Kalay, Hakan ; Stöckl, Johannes ; van Kooyk, Yvette ; den Haan, Joke M M
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-02, Vol.11 (2), p.183
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Phenotypic and Functional Properties of Human Steady State CD14.sup.+ and CD1a.sup.+ Antigen Presenting Cells and Epidermal Langerhans Cells
Author / Creator:Fehres, Cynthia. M ; Bruijns, Sven C. M ; Sotthewes, Brigit N ; Kalay, Hakan ; Schaffer, Lana ; Head, Steven R ; de Gruijl, Tanja D ; Garcia-Vallejo, Juan J ; van Kooyk, Yvette
Publisher:Public Library of Science
Journal title:PloS one, 2015-11, Vol.10 (11)
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In situ Delivery of Antigen to DC-SIGN super(+)CD14 super(+) Dermal Dendritic Cells Results in Enhanced CD8 super(+) T-Cell Responses
Author / Creator:Fehres, Cynthia M ; van Beelen, Astrid J ; Bruijns, Sven C M ; Ambrosini, Martino ; Kalay, Hakan ; Bloois, Louis van ; Unger, Wendy W J ; Garcia-Vallejo, Juan J ; Storm, Gert ; de Gruijl, Tanja D ; Kooyk, Yvette van
Journal title:Journal of investigative dermatology, 2015-09, Vol.135 (9), p.2228-2236
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Comparison of intradermal injection and epicutaneous laser microporation for anti-tumor vaccine delivery in a human skin explant model
Author / Creator:Duinkerken, Sanne ; Lubbers, Joyce ; Stolk, Dorian A ; Vree, Jana ; Ambrosini, Martino ; Kalay, Hakan ; Yvette Van Kooyk
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-12
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ReportsFull Text
Macrophage galactose-type lectin is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation
Author / Creator:Ilarregui, Juan M ; Kooij, Gijs ; Rodríguez, Ernesto ; van der Pol, Susanne M. A ; Koning, Nathalie ; Kalay, Hakan ; van der Horst, Joost C ; van Vliet, Sandra J ; García-Vallejo, Juan J ; de Vries, Helga E ; van Kooyk, Yvette
Publisher:BioMed Central Ltd
Journal title:Journal of Neuroinflammation, 2019, Vol.16 (1)
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ReportsFull Text
Phenotypic and Functional Properties of Human Steady State CD14.sup.+ and CD1a.sup.+ Antigen Presenting Cells and Epidermal Langerhans Cells
Author / Creator:Fehres, Cynthia. M ; Bruijns, Sven C. M ; Sotthewes, Brigit N ; Kalay, Hakan ; Schaffer, Lana ; Head, Steven R ; de Gruijl, Tanja D ; Garcia-Vallejo, Juan J ; van Kooyk, Yvette
Publisher:Public Library of Science
Journal title:PLoS ONE, 2015, Vol.10 (11)
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Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes

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Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells

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Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells

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Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

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Glycan modification of antigen alters its intracellular routing in dendritic cells, promoting priming of T cells

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Vaccination with DC-SIGN-Targeting αGC Liposomes Leads to Tumor Control, Irrespective of Suboptimally Activated T-Cells

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Optimization of Liposomes for Antigen Targeting to Splenic CD169 + Macrophages

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Phenotypic and Functional Properties of Human Steady State CD14+ and CD1a+ Antigen Presenting Cells and Epidermal Langerhans Cells

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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets

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849 Optimization of a GM3-containing liposomal vaccine that delivers antigen to CD169+ splenic macrophages

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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets

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Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy

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In situ Delivery of Tumor Antigen– and Adjuvant-Loaded Liposomes Boosts Antigen-Specific T-Cell Responses by Human Dermal Dendritic Cells

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In situ Delivery of Antigen to DC-SIGN+CD14+ Dermal Dendritic Cells Results in Enhanced CD8+ T-Cell Responses

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Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans

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Phenotypic and Functional Properties of Human Steady State CD14.sup.+ and CD1a.sup.+ Antigen Presenting Cells and Epidermal Langerhans Cells

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In situ Delivery of Antigen to DC-SIGN super(+)CD14 super(+) Dermal Dendritic Cells Results in Enhanced CD8 super(+) T-Cell Responses

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Comparison of intradermal injection and epicutaneous laser microporation for anti-tumor vaccine delivery in a human skin explant model

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Macrophage galactose-type lectin is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

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Phenotypic and Functional Properties of Human Steady State CD14.sup.+ and CD1a.sup.+ Antigen Presenting Cells and Epidermal Langerhans Cells

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