Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
About this item
Full title
Author / Creator
Li, Bo , Clohisey, Sara M. , Chia, Bing Shao , Wang, Bo , Cui, Ang , Eisenhaure, Thomas , Schweitzer, Lawrence D. , Hoover, Paul , Parkinson, Nicholas J. , Nachshon, Aharon , Smith, Nikki , Regan, Tim , Farr, David , Gutmann, Michael U. , Bukhari, Syed Irfan , Law, Andrew , Sangesland, Maya , Gat-Viks, Irit , Digard, Paul , Vasudevan, Shobha , Lingwood, Daniel , Dockrell, David H. , Doench, John G. , Baillie, J. Kenneth and Hacohen, Nir
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Host dependency factors that are required for influenza A virus infection may serve as therapeutic targets as the virus is less likely to bypass them under drug-mediated selection pressure. Previous attempts to identify host factors have produced largely divergent results, with few overlapping hits across different studies. Here, we perform a genom...
Alternative Titles
Full title
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
Authors, Artists and Contributors
Author / Creator
Clohisey, Sara M.
Chia, Bing Shao
Wang, Bo
Cui, Ang
Eisenhaure, Thomas
Schweitzer, Lawrence D.
Hoover, Paul
Parkinson, Nicholas J.
Nachshon, Aharon
Smith, Nikki
Regan, Tim
Farr, David
Gutmann, Michael U.
Bukhari, Syed Irfan
Law, Andrew
Sangesland, Maya
Gat-Viks, Irit
Digard, Paul
Vasudevan, Shobha
Lingwood, Daniel
Dockrell, David H.
Doench, John G.
Baillie, J. Kenneth
Hacohen, Nir
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c1f734a4d6574c6d950eb373c2f18352
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c1f734a4d6574c6d950eb373c2f18352
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13965-x
