Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Expression of active c-Abl in adult mouse forebrain neurons in the AblPP/tTA mice resulted in severe neurodegeneration, particularly in the CA1 region of the hippocampus. Neuronal loss was preceded and accompanied by substantial microgliosis and astrocytosis. In contrast, expression of constitutively active Arg (Abl-related gene) in mouse forebrain...
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Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
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TN_cdi_doaj_primary_oai_doaj_org_article_c221e041596d4863b9a61e3dcc48e912
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c221e041596d4863b9a61e3dcc48e912
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/1742-2094-9-208
