Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae
Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae
About this item
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Author / Creator
Rother, Christine , Uhlmann, Ruth E. , Müller, Stephan A. , Schelle, Juliane , Skodras, Angelos , Obermüller, Ulrike , Häsler, Lisa M. , Lambert, Marius , Baumann, Frank , Xu, Ying , Bergmann, Carina , Salvadori, Giulia , Loos, Maarten , Brzak, Irena , Shimshek, Derya , Neumann, Ulf , Walker, Lary C. , Schultz, Stephanie A. , Chhatwal, Jasmeer P. , Kaeser, Stephan A. , Lichtenthaler, Stefan F. , Staufenbiel, Matthias , Jucker, Mathias and Dominantly Inherited Alzheimer Network
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Brain Aβ deposition is a key early event in the pathogenesis of Alzheimer´s disease (AD), but the long presymptomatic phase and poor correlation between Aβ deposition and clinical symptoms remain puzzling. To elucidate the dependency of downstream pathologies on Aβ, we analyzed the trajectories of cerebral Aβ accumulation, Aβ seeding activity, and...
Alternative Titles
Full title
Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae
Authors, Artists and Contributors
Author / Creator
Uhlmann, Ruth E.
Müller, Stephan A.
Schelle, Juliane
Skodras, Angelos
Obermüller, Ulrike
Häsler, Lisa M.
Lambert, Marius
Baumann, Frank
Xu, Ying
Bergmann, Carina
Salvadori, Giulia
Loos, Maarten
Brzak, Irena
Shimshek, Derya
Neumann, Ulf
Walker, Lary C.
Schultz, Stephanie A.
Chhatwal, Jasmeer P.
Kaeser, Stephan A.
Lichtenthaler, Stefan F.
Staufenbiel, Matthias
Jucker, Mathias
Dominantly Inherited Alzheimer Network
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c331575d738c441aa6d10bc637786581
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c331575d738c441aa6d10bc637786581
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-34538-5
