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Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine re...

Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3dabdbbc9174f55a2075fc232a9841e

Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine renal carcinoma model

About this item

Full title

Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine renal carcinoma model

Publisher

England: BMJ Publishing Group Ltd

Journal title

Journal for immunotherapy of cancer, 2021-12, Vol.9 (12), p.e003101

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

BackgroundInduction of CD8+ T cells that recognize immunogenic, mutated protein fragments in the context of major histocompatibility class I (MHC-I) is a pressing challenge for cancer vaccine development.MethodsUsing the commonly used murine renal adenocarcinoma RENCA cancer model, MHC-I restricted neoepitopes are predicted following next-generatio...

Alternative Titles

Full title

Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine renal carcinoma model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c3dabdbbc9174f55a2075fc232a9841e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3dabdbbc9174f55a2075fc232a9841e

Other Identifiers

ISSN

2051-1426

E-ISSN

2051-1426

DOI

10.1136/jitc-2021-003101

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