Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers
Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop receptor family are key players in fast signal transduction throughout the nervous system. They have been shown to be modulated by the lipid environment, however the underlying mechanism is not well understood. We report three structures of the Cys-loop 5-HT
3A
serotonin receptor (...
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Full title
Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers
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TN_cdi_doaj_primary_oai_doaj_org_article_c3dc1144479e42dfbcbc8d743307e558
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3dc1144479e42dfbcbc8d743307e558
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21016-7
