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Structure and activation of pro-activin A

Structure and activation of pro-activin A

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4019a3eef784171add443f375d74943

Structure and activation of pro-activin A

About this item

Full title

Structure and activation of pro-activin A

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-07, Vol.7 (1), p.12052-12052, Article 12052

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Activins are growth factors with multiple roles in the development and homeostasis. Like all TGF-β family of growth factors, activins are synthesized as large precursors from which mature dimeric growth factors are released proteolytically. Here we have studied the activation of activin A and determined crystal structures of the unprocessed precurs...

Alternative Titles

Full title

Structure and activation of pro-activin A

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c4019a3eef784171add443f375d74943

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4019a3eef784171add443f375d74943

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms12052

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