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Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervic...

Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c40d0acc9bc143a3b670401e65c9c657

Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

About this item

Full title

Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-05, Vol.13 (1), p.2563-2563, Article 2563

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Integration of human papillomavirus (HPV) DNA into the human genome is considered as a key event in cervical carcinogenesis. Here, we perform comprehensive characterization of large-range virus-human integration events in 16 HPV16-positive cervical tumors using the Nanopore long-read sequencing technology. Four distinct integration types characteri...

Alternative Titles

Full title

Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c40d0acc9bc143a3b670401e65c9c657

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c40d0acc9bc143a3b670401e65c9c657

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-30190-1

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