Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervic...
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
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Author / Creator
Zhou, Liyuan , Qiu, Qiongzi , Zhou, Qing , Li, Jianwei , Yu, Mengqian , Li, Kezhen , Xu, Lingling , Ke, Xiaohui , Xu, Haiming , Lu, Bingjian , Wang, Hui , Lu, Weiguo , Liu, Pengyuan and Lu, Yan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Integration of human papillomavirus (HPV) DNA into the human genome is considered as a key event in cervical carcinogenesis. Here, we perform comprehensive characterization of large-range virus-human integration events in 16 HPV16-positive cervical tumors using the Nanopore long-read sequencing technology. Four distinct integration types characteri...
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Full title
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c40d0acc9bc143a3b670401e65c9c657
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c40d0acc9bc143a3b670401e65c9c657
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30190-1