Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheim...
Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer’s disease mouse model
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The defining features of Alzheimer’s disease (AD) include alterations in protein aggregation, immunity, lipid metabolism, synapses, and learning and memory. Of these, lipid abnormalities are the least understood. Here, we investigate the role of Stearoyl-CoA desaturase (SCD), a crucial regulator of fatty acid desaturation, in AD pathogenesis. We sh...
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Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer’s disease mouse model
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TN_cdi_doaj_primary_oai_doaj_org_article_c4156f3f019a4fb582af55e7362fab88
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4156f3f019a4fb582af55e7362fab88
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29506-y
