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Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early...

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c43c93b76df74ebbb83d778241a75b5d

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

About this item

Full title

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Publisher

Cambridge: eLife Sciences Publications Ltd

Journal title

eLife, 2023-10, Vol.12

Language

English

Formats

Publication information

Publisher

Cambridge: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Despite their promise, circulating tumor DNA (ctDNA)-based assays for multi-cancer early detection face challenges in test performance, due mostly to the limited abundance of ctDNA and its inherent variability. To address these challenges, published assays to date demanded a very high-depth sequencing, resulting in an elevated price of test. Herein...

Alternative Titles

Full title

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c43c93b76df74ebbb83d778241a75b5d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c43c93b76df74ebbb83d778241a75b5d

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.89083

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