Endogenous Retroviruses Walk a Fine Line between Priming and Silencing
Endogenous Retroviruses Walk a Fine Line between Priming and Silencing
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
Endogenous retroviruses (ERVs) in mammals are closely related to infectious retroviruses and utilize host tRNAs as a primer for reverse transcription and replication, a hallmark of long terminal repeat (LTR) retroelements. Their dependency on tRNA makes these elements vulnerable to targeting by small RNAs derived from the 3'-end of mature tRNAs (3'...
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Endogenous Retroviruses Walk a Fine Line between Priming and Silencing
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TN_cdi_doaj_primary_oai_doaj_org_article_c52230bba8c2492c93d58bc948dbb736
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c52230bba8c2492c93d58bc948dbb736
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ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v12080792