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PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c585d389c6de449fb42759c3f714e5e9

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

About this item

Full title

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-09, Vol.8 (1), p.672-14, Article 672

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Polycomb repressive complex 2 and the epigenetic mark that it deposits, H3K27me3, are evolutionarily conserved and play critical roles in development and cancer. However, their roles in cell fate decisions in early embryonic development remain poorly understood. Here we report that knockout of polycomb repressive complex 2 genes in human embryonic...

Alternative Titles

Full title

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c585d389c6de449fb42759c3f714e5e9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c585d389c6de449fb42759c3f714e5e9

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00668-4

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