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Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies...

Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c5c1da08d4014458bca5479e40d5cf1c

Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

About this item

Full title

Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-02, Vol.11 (1), p.896-896, Article 896

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Predicting the outcome of immunotherapy treatment in melanoma patients is challenging. Alterations in genes involved in antigen presentation and the interferon gamma (IFNγ) pathway play an important role in the immune response to tumors. We describe here that the overexpression of
PSMB8
and
PSMB9
, two major components of the immunoprot...

Alternative Titles

Full title

Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c5c1da08d4014458bca5479e40d5cf1c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c5c1da08d4014458bca5479e40d5cf1c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-14639-9

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