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HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein...

HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c5dafdb0e7784bf385a1b6e13e196c8e

HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade

About this item

Full title

HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade

Publisher

England: BioMed Central Ltd

Journal title

Molecular cancer, 2011-04, Vol.10 (1), p.43-43, Article 43

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Oxidative stress has been implicated in the pathogenesis of a wide spectrum of human diseases, including Hepatitis B virus (HBV)-related liver disease. Hepatitis B virus X protein (HBx) is a key regulator of HBV that exerts pleiotropic activity on cellular functions. Recent studies showed that HBx alters mitochondrial membrane potential, thereby se...

Alternative Titles

Full title

HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c5dafdb0e7784bf385a1b6e13e196c8e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c5dafdb0e7784bf385a1b6e13e196c8e

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/1476-4598-10-43

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