Psychological Stress Deteriorates Skin Barrier Function by Activating 11β-Hydroxysteroid Dehydrogena...
Psychological Stress Deteriorates Skin Barrier Function by Activating 11β-Hydroxysteroid Dehydrogenase 1 and the HPA Axis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Psychological stress (PS) increases endogenous glucocorticoids (GC) by activating the hypothalamic-pituitary-adrenal axis. The negative effects of GC on skin barrier function under PS have been well-established. However, endogenous GC can also be active when cortisone (inactive form) is converted to cortisol (active form) by 11β-hydroxysteroid dehy...
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Full title
Psychological Stress Deteriorates Skin Barrier Function by Activating 11β-Hydroxysteroid Dehydrogenase 1 and the HPA Axis
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TN_cdi_doaj_primary_oai_doaj_org_article_c63014c69806416591aa3da08f51350b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c63014c69806416591aa3da08f51350b
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-24653-z
