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APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in co...

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c691f60e95844b5ab184a43042c094dc

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly

About this item

Full title

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly

Publisher

England: BioMed Central

Journal title

Alzheimer's research & therapy, 2023-04, Vol.15 (1), p.71-15, Article 71

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Neuroinflammation, characterized by increased reactivity of microglia and astrocytes in the brain, is known to be present at various stages of the Alzheimer's disease (AD) continuum. However, its presence and relationship with amyloid pathology in cognitively normal at-risk individuals is less clear. Here, we used positron emission tomography (PET)...

Alternative Titles

Full title

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c691f60e95844b5ab184a43042c094dc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c691f60e95844b5ab184a43042c094dc

Other Identifiers

ISSN

1758-9193

E-ISSN

1758-9193

DOI

10.1186/s13195-023-01209-6

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