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Evaluation of Molecular Simulations and Deep Learning Prediction of Antibodies' Recognition of TRBC1...

Evaluation of Molecular Simulations and Deep Learning Prediction of Antibodies' Recognition of TRBC1...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c6c65b603a794f79b39d5d2263a6482d

Evaluation of Molecular Simulations and Deep Learning Prediction of Antibodies' Recognition of TRBC1 and TRBC2

About this item

Full title

Evaluation of Molecular Simulations and Deep Learning Prediction of Antibodies' Recognition of TRBC1 and TRBC2

Publisher

Switzerland: MDPI AG

Journal title

Antibodies (Basel), 2023-09, Vol.12 (3), p.58

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

T cell receptor β-chain constant (TRBC) is a promising class of cancer targets consisting of two highly homologous proteins, TRBC1 and TRBC2. Developing targeted antibody therapeutics against TRBC1 or TRBC2 is expected to eradicate the malignant T cells and preserve half of the normal T cells. Recently, several antibody engineering strategies have...

Alternative Titles

Full title

Evaluation of Molecular Simulations and Deep Learning Prediction of Antibodies' Recognition of TRBC1 and TRBC2

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c6c65b603a794f79b39d5d2263a6482d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c6c65b603a794f79b39d5d2263a6482d

Other Identifiers

ISSN

2073-4468

E-ISSN

2073-4468

DOI

10.3390/antib12030058

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