Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
XX
female and
XY
male therian mammals equalize X-linked gene expression through the mitotically-stable transcriptional inactivation of one of the two X chromosomes in female somatic cells. Here, we describe an essential function of the X-linked homolog of an ancestral X-Y gene pair,
Kdm5c
-
Kdm5d
, in the expression of Xist lnc...
Alternative Titles
Full title
Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
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TN_cdi_doaj_primary_oai_doaj_org_article_c7bf99de72cb4d26b0b6c0c4c1912e66
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7bf99de72cb4d26b0b6c0c4c1912e66
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30352-1
