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Spt5 orchestrates cryptic transcript suppression and transcriptional directionality

Spt5 orchestrates cryptic transcript suppression and transcriptional directionality

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8a0e68d5d4c4d97a1ab1b60ab1cd4ba

Spt5 orchestrates cryptic transcript suppression and transcriptional directionality

About this item

Full title

Spt5 orchestrates cryptic transcript suppression and transcriptional directionality

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2024-10, Vol.7 (1), p.1370-14, Article 1370

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Spt5 is a well-conserved factor that manipulates multiple stages of transcription from promoter-proximal pausing (PPP) to termination. Recent studies have revealed an unexpected increase of antisense transcripts near promoters in cells expressing mutant Spt5. Here, we identify Spt5p-restricted intragenic antisense transcripts and their close relati...

Alternative Titles

Full title

Spt5 orchestrates cryptic transcript suppression and transcriptional directionality

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c8a0e68d5d4c4d97a1ab1b60ab1cd4ba

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8a0e68d5d4c4d97a1ab1b60ab1cd4ba

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-024-07014-7

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