Spt5 orchestrates cryptic transcript suppression and transcriptional directionality
Spt5 orchestrates cryptic transcript suppression and transcriptional directionality
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Spt5 is a well-conserved factor that manipulates multiple stages of transcription from promoter-proximal pausing (PPP) to termination. Recent studies have revealed an unexpected increase of antisense transcripts near promoters in cells expressing mutant Spt5. Here, we identify Spt5p-restricted intragenic antisense transcripts and their close relati...
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Spt5 orchestrates cryptic transcript suppression and transcriptional directionality
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TN_cdi_doaj_primary_oai_doaj_org_article_c8a0e68d5d4c4d97a1ab1b60ab1cd4ba
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8a0e68d5d4c4d97a1ab1b60ab1cd4ba
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2399-3642
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2399-3642
DOI
10.1038/s42003-024-07014-7