Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA da...
Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response
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Publisher
Germany: BioMed Central Ltd
Journal title
Language
English
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Publisher
Germany: BioMed Central Ltd
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Contents
Cardiac fibrosis is the hallmark of all forms of chronic heart disease. Activation and proliferation of cardiac fibroblasts are the prime mediators of cardiac fibrosis. Existing studies show that ROS and inflammatory cytokines produced during fibrosis not only signal proliferative stimuli but also contribute to DNA damage. Therefore, as a prerequis...
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Full title
Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response
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TN_cdi_doaj_primary_oai_doaj_org_article_c9732583a636444882ccab2ad924f6f6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9732583a636444882ccab2ad924f6f6
Other Identifiers
ISSN
1868-7083,1868-7075
E-ISSN
1868-7083
DOI
10.1186/s13148-024-01719-6
