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ArticlesPeer ReviewedFull Text
High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis
Author / Creator:Xu, Xingbo ; Tan, Xiaoying ; Tampe, Björn ; Wilhelmi, Tim ; Hulshoff, Melanie S. ; Saito, Shoji ; Moser, Tobias ; Kalluri, Raghu ; Hasenfuss, Gerd ; Zeisberg, Elisabeth M. ; Zeisberg, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3509-15, Article 3509
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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
Author / Creator:Zeisberg, Elisabeth M ; Tarnavski, Oleg ; Zeisberg, Michael ; Dorfman, Adam L ; McMullen, Julie R ; Gustafsson, Erika ; Chandraker, Anil ; Yuan, Xueli ; Pu, William T ; Roberts, Anita B ; Neilson, Eric G ; Sayegh, Mohamed H ; Izumo, Seigo ; Kalluri, Raghu
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2007-08, Vol.13 (8), p.952-961
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CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications
Author / Creator:Xu, Xingbo ; Hulshoff, Melanie S. ; Tan, Xiaoying ; Zeisberg, Michael ; Zeisberg, Elisabeth M.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-04, Vol.21 (9), p.3038
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Evidence for antifibrotic incretin-independent effects of the DPP-4 inhibitor linagliptin
Author / Creator:Zeisberg, Michael ; Zeisberg, Elisabeth M.
Publisher:United States: Elsevier Inc
Journal title:Kidney international, 2015-09, Vol.88 (3), p.429-431
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DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition
Author / Creator:Tan, Xiaoying ; Xu, Xingbo ; Zeisberg, Michael ; Zeisberg, Elisabeth M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-01, Vol.11 (1), p.e0147816-e0147816
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miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus
Author / Creator:Hulshoff, Melanie S. ; Schellinger, Isabel N. ; Xu, Xingbo ; Fledderus, Jolien ; Rath, Sandip K. ; Wong, Fang Cheng ; Maamari, Sabine ; Haunschild, Josephina ; Krenning, Guido ; Raaz, Uwe ; Zeisberg, Elisabeth M.
Publisher:England: BioMed Central Ltd
Journal title:Diabetology and metabolic syndrome, 2023-01, Vol.15 (1), p.11-11, Article 11
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PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation
Author / Creator:Nyamsuren, Gunsmaa ; Rapp, Gregor ; Dihazi, Hassan ; Zeisberg, Elisabeth M. ; Tampe, Desiree ; Tampe, Björn ; Zeisberg, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-12, Vol.11 (1), p.24075-24075, Article 24075
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Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis
Author / Creator:Backhaus, Sören J. ; Lange, Torben ; Beuthner, Bo Eric ; Topci, Rodi ; Wang, Xiaoqing ; Kowallick, Johannes T. ; Lotz, Joachim ; Seidler, Tim ; Toischer, Karl ; Zeisberg, Elisabeth M. ; Puls, Miriam ; Jacobshagen, Claudius ; Uecker, Martin ; Hasenfuß, Gerd ; Schuster, Andreas
Publisher:England: BioMed Central Ltd
Journal title:Journal of cardiovascular magnetic resonance, 2020-06, Vol.22 (1), p.46-46, Article 46
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Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response
Author / Creator:Rath, Sandip Kumar ; Nyamsuren, Gunsmaa ; Tampe, Björn ; Yu, David Sung-wen ; Hulshoff, Melanie S. ; Schlösser, Denise ; Maamari, Sabine ; Zeisberg, Michael ; Zeisberg, Elisabeth M.
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2024-08, Vol.16 (1), p.119-20, Article 119
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Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis
Author / Creator:Kanwischer, Leon ; Xu, Xingbo ; Saifuddin, Afifa Binta ; Maamari, Sabine ; Tan, Xiaoying ; Alnour, Fouzi ; Tampe, Björn ; Meyer, Thomas ; Zeisberg, Michael ; Hasenfuss, Gerd ; Puls, Miriam ; Zeisberg, Elisabeth M.
Publisher:London: BioMed Central Ltd
Journal title:Clinical epigenetics, 2023-09, Vol.15 (1), p.1-14, Article 149
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ArticlesPeer ReviewedFull Text
Morphogenesis of the right ventricle requires myocardial expression of Gata4
Author / Creator:Zeisberg, Elisabeth M. ; Ma, Qing ; Juraszek, Amy L. ; Moses, Kelvin ; Schwartz, Robert J. ; Izumo, Seigo ; Pu, William T.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2005-06, Vol.115 (6), p.1522-1531
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ArticlesPeer ReviewedFull Text
Hepatic Interferon-λ3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C
Author / Creator:Amanzada, Ahmad ; Reinhardt, Lars ; Fey, Dorothea ; Zeisberg, Elisabeth M. ; Mihm, Sabine
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-11, Vol.10 (11), p.e0143783-e0143783
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ArticlesPeer ReviewedFull Text
Aortic valve calcification and myocardial fibrosis determine outcome following transcatheter aortic valve replacement
Author / Creator:Evertz, Ruben ; Hub, Sebastian ; Beuthner, Bo Eric ; Backhaus, Sören J. ; Lange, Torben ; Schulz, Alexander ; Toischer, Karl ; Seidler, Tim ; Haehling, Stephan ; Puls, Miriam ; Kowallick, Johannes T. ; Zeisberg, Elisabeth M. ; Hasenfuß, Gerd ; Schuster, Andreas
Publisher:England: John Wiley & Sons, Inc
Journal title:ESC Heart Failure, 2023-08, Vol.10 (4), p.2307-2318
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Interdisciplinary Research on Aortic Valve Stenosis: A Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement
Author / Creator:Beuthner, Bo E. C. ; Topci, Rodi ; Derks, Mareike ; Franke, Thomas ; Seelke, Sandra ; Puls, Miriam ; Schuster, Andreas ; Toischer, Karl ; Valentova, Miroslava ; Cyganek, Lukas ; Zeisberg, Elisabeth M. ; Jacobshagen, Claudius ; Hasenfuss, Gerd ; Nussbeck, Sara Y.
Publisher:Ubiquity Press Ltd
Journal title:Open journal of bioresources, 2020-03, Vol.7 (9540)
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ArticlesPeer ReviewedFull Text
Methylation determines fibroblast activation and fibrogenesis in the kidney
Author / Creator:Bechtel, Wibke ; McGoohan, Scott ; Zeisberg, Elisabeth M ; Müller, Gerhard A ; Kalbacher, Hubert ; Salant, David J ; Müller, Claudia A ; Kalluri, Raghu ; Zeisberg, Michael
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2010-05, Vol.16 (5), p.544-550
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Circulating Endoglin Concentration Is Not Elevated in Chronic Kidney Disease
Author / Creator:Charytan, David M. ; Helfand, Alexander M. ; MacDonald, Brian A. ; Cinelli, Angeles ; Kalluri, Raghu ; Zeisberg, Elisabeth M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e23718-e23718
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Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1
Author / Creator:Wilhelmi, Tim ; Xu, Xingbo ; Tan, Xiaoying ; Hulshoff, Melanie S. ; Maamari, Sabine ; Sossalla, Samuel ; Zeisberg, Michael ; Zeisberg, Elisabeth M.
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (9), p.3905-3924
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Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure
Author / Creator:Tampe, Björn ; Tampe, Désirée ; Nyamsuren, Gunsmaa ; Klöpper, Friederike ; Rapp, Gregor ; Kauffels, Anne ; Lorf, Thomas ; Zeisberg, Elisabeth M. ; Müller, Gerhard A. ; Kalluri, Raghu ; Hakroush, Samy ; Zeisberg, Michael
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-07, Vol.128 (7), p.3053-3070
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ArticlesPeer ReviewedFull Text
Precision renal medicine: a roadmap towards targeted kidney fibrosis therapies
Author / Creator:Zeisberg, Michael ; Zeisberg, Elisabeth M.
Publisher:England: BioMed Central Ltd
Journal title:Fibrogenesis & tissue repair, 2015-09, Vol.8 (1), p.16-16, Article 16
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Estimating myocardial fibrosis in aortic stenosis using the serum collagen type I C‐terminal telopeptide to matrix metalloproteinase‐1 ratio
Author / Creator:Gersch, Svante ; Bengel, Philipp ; Paul, Niels B. ; Ravassa, Susana ; Haehling, Stephan ; Fischer, Andreas ; Zeisberg, Elisabeth M. ; Puls, Miriam ; Hasenfuß, Gerd ; Schnelle, Moritz
Publisher:China: John Wiley & Sons, Inc
Journal title:MedComm (2020), 2025-02, Vol.6 (2), p.e70069-n/a
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Showing 1 to 20 of 24 results

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High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications

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Evidence for antifibrotic incretin-independent effects of the DPP-4 inhibitor linagliptin

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DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition

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miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus

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PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation

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Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis

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Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response

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Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis

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Morphogenesis of the right ventricle requires myocardial expression of Gata4

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Hepatic Interferon-λ3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C

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Aortic valve calcification and myocardial fibrosis determine outcome following transcatheter aortic valve replacement

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Interdisciplinary Research on Aortic Valve Stenosis: A Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement

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Methylation determines fibroblast activation and fibrogenesis in the kidney

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Circulating Endoglin Concentration Is Not Elevated in Chronic Kidney Disease

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Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1

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Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure

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Precision renal medicine: a roadmap towards targeted kidney fibrosis therapies

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Estimating myocardial fibrosis in aortic stenosis using the serum collagen type I C‐terminal telopeptide to matrix metalloproteinase‐1 ratio

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