Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via Adipo...
Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway
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England: BioMed Central
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English
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England: BioMed Central
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Microglia-mediated neuroinflammation is important in Alzheimer's disease (AD) pathogenesis. Extracellular deposition of β-amyloid (Aβ), a major pathological hallmark of AD, can induce microglia activation. Adiponectin (APN), an adipocyte-derived adipokine, exerts anti-inflammatory effects in the periphery and brain. Chronic APN deficiency leads to...
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Full title
Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_c9b9947da2c14f84a6e7ae1a0733a277
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c9b9947da2c14f84a6e7ae1a0733a277
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-019-1492-6
