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IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells

IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca2a07d5bd2742a9bb7316e542e77726

IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells

About this item

Full title

IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells

Publisher

England: BioMed Central

Journal title

Molecular medicine (Cambridge, Mass.), 2017-01, Vol.23 (1), p.83-91

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Calcific aortic valve disease (CAVD) is common among the elderly, and aortic valve interstitial cells (AVICs) exhibit unique inflammatory and osteogenic responses to pro-inflammatory stimulation which play an important role in valvular fibrosis and calcification. Thus, suppression of AVIC pro-inflammatory response may have therapeutic utility for p...

Alternative Titles

Full title

IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ca2a07d5bd2742a9bb7316e542e77726

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca2a07d5bd2742a9bb7316e542e77726

Other Identifiers

ISSN

1076-1551

E-ISSN

1528-3658

DOI

10.2119/molmed.2017.00022

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