Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with respon...
Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy
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Author / Creator
Turiello, Roberta , Capone, Mariaelena , Giannarelli, Diana , Morretta, Elva , Monti, Maria Chiara , Madonna, Gabriele , Mallardo, Domenico , Festino, Lucia , Azzaro, Rosa , Levesque, Mitchell P , Imhof, Laurence , Weide, Benjamin , Amaral, Teresa , Chevrier, Marc , Sucker, Antje , Rutkowski, Piotr , Schadendorf, Dirk , Lebbe, Celeste , Luke, Jason John , Wistuba-Hamprecht, Kilian , Dummer, Reinhard , Pinto, Aldo , Morello, Silvana and Ascierto, Paolo A
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd
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Scope and Contents
Contents
BackgroundInhibitors of immune checkpoint programmed cell death protein 1 (PD-1) receptor on T cells have shown remarkable clinical outcomes in metastatic melanoma. However, most patients are resistant to therapy. Production of extracellular adenosine, via CD73-mediated catabolism of AMP, contributes to suppress T-cell-mediated responses against ca...
Alternative Titles
Full title
Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy
Authors, Artists and Contributors
Author / Creator
Capone, Mariaelena
Giannarelli, Diana
Morretta, Elva
Monti, Maria Chiara
Madonna, Gabriele
Mallardo, Domenico
Festino, Lucia
Azzaro, Rosa
Levesque, Mitchell P
Imhof, Laurence
Weide, Benjamin
Amaral, Teresa
Chevrier, Marc
Sucker, Antje
Rutkowski, Piotr
Schadendorf, Dirk
Lebbe, Celeste
Luke, Jason John
Wistuba-Hamprecht, Kilian
Dummer, Reinhard
Pinto, Aldo
Morello, Silvana
Ascierto, Paolo A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ca411bc46b9f4db2a7c3cf284f8adfd0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ca411bc46b9f4db2a7c3cf284f8adfd0
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001689
