Inducible and reversible inhibition of miRNA-mediated gene repression in vivo
Inducible and reversible inhibition of miRNA-mediated gene repression in vivo
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Author / Creator
La Rocca, Gaspare , King, Bryan , Shui, Bing , Li, Xiaoyi , Zhang, Minsi , Akat, Kemal M , Ogrodowski, Paul , Mastroleo, Chiara , Chen, Kevin , Cavalieri, Vincenzo , Ma, Yilun , Anelli, Viviana , Betel, Doron , Vidigal, Joana , Tuschl, Thomas , Meister, Gunter , Thompson, Craig B , Lindsten, Tullia , Haigis, Kevin and Ventura, Andrea
Publisher
England: eLife Sciences Publications Ltd
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English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Although virtually all gene networks are predicted to be controlled by miRNAs, the contribution of this important layer of gene regulation to tissue homeostasis in adult animals remains unclear. Gain and loss-of-function experiments have provided key insights into the specific function of individual miRNAs, but effective genetic tools to study the...
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Full title
Inducible and reversible inhibition of miRNA-mediated gene repression in vivo
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TN_cdi_doaj_primary_oai_doaj_org_article_caa7c7e535be45199b348ce0b4f5658f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_caa7c7e535be45199b348ce0b4f5658f
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.70948
