Targeting Beta-Amyloid at the CSF: A New Therapeutic Strategy in Alzheimer's Disease
Targeting Beta-Amyloid at the CSF: A New Therapeutic Strategy in Alzheimer's Disease
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Although immunotherapies against the amyloid-β (Aβ) peptide tried so date failed to prove sufficient clinical benefit, Aβ still remains the main target in Alzheimer's disease (AD). This article aims to show the rationale of a new therapeutic strategy: clearing Aβ from the CSF continuously (the "CSF-sink" therapeutic strategy). First, we describe th...
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Targeting Beta-Amyloid at the CSF: A New Therapeutic Strategy in Alzheimer's Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_ccbb91f7f49c407cb2fc1b9f2aef5906
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ccbb91f7f49c407cb2fc1b9f2aef5906
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2018.00100
