Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthe...
Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthetic injector E. coli strain
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Bacterial type III secretion systems (T3SSs) assemble a multiprotein complex termed the injectisome, which acts as a molecular syringe for translocation of specific effector proteins into the cytoplasm of host cells. The use of injectisomes for delivery of therapeutic proteins into mammalian cells is attractive for biomedical applications. With tha...
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Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthetic injector E. coli strain
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TN_cdi_doaj_primary_oai_doaj_org_article_cd00e94d69614c2ea65558afea0e5aaa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd00e94d69614c2ea65558afea0e5aaa
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ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-022-01860-y