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Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthe...

Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd00e94d69614c2ea65558afea0e5aaa

Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthetic injector E. coli strain

About this item

Full title

Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthetic injector E. coli strain

Publisher

London: BioMed Central Ltd

Journal title

Microbial cell factories, 2022-07, Vol.21 (1), p.1-133, Article 133

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Bacterial type III secretion systems (T3SSs) assemble a multiprotein complex termed the injectisome, which acts as a molecular syringe for translocation of specific effector proteins into the cytoplasm of host cells. The use of injectisomes for delivery of therapeutic proteins into mammalian cells is attractive for biomedical applications. With tha...

Alternative Titles

Full title

Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthetic injector E. coli strain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_cd00e94d69614c2ea65558afea0e5aaa

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd00e94d69614c2ea65558afea0e5aaa

Other Identifiers

ISSN

1475-2859

E-ISSN

1475-2859

DOI

10.1186/s12934-022-01860-y

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