ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
About this item
Full title
Author / Creator
Fischer, Robert J. , van Doremalen, Neeltje , Adney, Danielle R. , Yinda, Claude Kwe , Port, Julia R. , Holbrook, Myndi G. , Schulz, Jonathan E. , Williamson, Brandi N. , Thomas, Tina , Barbian, Kent , Anzick, Sarah L. , Ricklefs, Stacy , Smith, Brian J. , Long, Dan , Martens, Craig , Saturday, Greg , de Wit, Emmie , Gilbert, Sarah C. , Lambe, Teresa and Munster, Vincent J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
We investigated ChAdOx1 nCoV-19 (AZD1222) vaccine efficacy against SARS-CoV-2 variants of concern (VOCs) B.1.1.7 and B.1.351 in Syrian hamsters. We previously showed protection against SARS-CoV-2 disease and pneumonia in hamsters vaccinated with a single dose of ChAdOx1 nCoV-19. Here, we observe a 9.5-fold reduction of virus neutralizing antibody t...
Alternative Titles
Full title
ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7
Authors, Artists and Contributors
Author / Creator
van Doremalen, Neeltje
Adney, Danielle R.
Yinda, Claude Kwe
Port, Julia R.
Holbrook, Myndi G.
Schulz, Jonathan E.
Williamson, Brandi N.
Thomas, Tina
Barbian, Kent
Anzick, Sarah L.
Ricklefs, Stacy
Smith, Brian J.
Long, Dan
Martens, Craig
Saturday, Greg
de Wit, Emmie
Gilbert, Sarah C.
Lambe, Teresa
Munster, Vincent J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_cd521c32186f4059b6298768dcc0d51a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cd521c32186f4059b6298768dcc0d51a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26178-y
